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Current status of HER2 testing: caught between a rock and a hard place.

作者信息

Schnitt S J, Jacobs T W

机构信息

Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

出版信息

Am J Clin Pathol. 2001 Dec;116(6):806-10. doi: 10.1309/WMN8-VTR5-DUGF-X12L.

DOI:10.1309/WMN8-VTR5-DUGF-X12L
PMID:11764067
Abstract
摘要

相似文献

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Current status of HER2 testing: caught between a rock and a hard place.
Am J Clin Pathol. 2001 Dec;116(6):806-10. doi: 10.1309/WMN8-VTR5-DUGF-X12L.
2
Luminal B breast tumors are not HER2 positive.管腔B型乳腺肿瘤不是HER2阳性。
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Human epidermal growth factor receptor 2 testing in breast cancer.乳腺癌中的人表皮生长因子受体2检测
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The clinical evaluation of HER-2 status: which test to use?HER-2状态的临床评估：应使用哪种检测方法？
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Comparison of immunohistochemical and fluorescence in situ hybridization assessment of HER-2 status in routine practice.
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Fluorescent in situ hybridization as a primary test for HER2 status in breast cancer: controversies.荧光原位杂交作为乳腺癌HER2状态的主要检测方法：争议
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Re: How do you tell whether a breast cancer is HER2 positive? Ongoing studies keep debate in high gear.关于：如何判断乳腺癌是否为HER2阳性？正在进行的研究使这场争论持续激烈。
J Natl Cancer Inst. 2011 Apr 20;103(8):698-9. doi: 10.1093/jnci/djr074. Epub 2011 Mar 15.
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[Quality assured HER2 analysis in breast cancer. Important therapeutic predictive and prognostic factor].[乳腺癌中质量有保证的HER2分析。重要的治疗预测和预后因素]
Lakartidningen. 2008;105(32-33):2181-4.
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The importance of accuracy in HER2 testing.
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The quality of Her-2/Neu predictive immunohistochemistry: something FISHy?Her-2/Neu预测性免疫组织化学的质量：有点像鱼腥味的事？ （此翻译仅供参考，具体含义需结合专业背景进一步理解，原标题可能是带有一定双关或隐喻的表述）
Mod Pathol. 2000 Jan;13(1):1-3. doi: 10.1038/modpathol.3880001.

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Targeting HER2-positive breast cancer: advances and future directions.针对 HER2 阳性乳腺癌：进展与未来方向。
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Correlation of Immunohistochemistry and Fluorescence Hybridization for HER-2 Assessment in Breast Cancer Patients: Single Centre Experience.免疫组织化学与荧光杂交技术在乳腺癌患者HER-2评估中的相关性：单中心经验
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A novel quantitative immunohistochemistry method for precise protein measurements directly in formalin-fixed, paraffin-embedded specimens: analytical performance measuring HER2.
一种直接在福尔马林固定、石蜡包埋标本中进行精确蛋白质测量的新型定量免疫组织化学方法：测量HER2的分析性能
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Concomitant detection of HER2 protein and gene alterations by immunohistochemistry (IHC) and silver enhanced in situ hybridization (SISH) identifies HER2 positive breast cancer with and without gene amplification.通过免疫组织化学（IHC）和银增强原位杂交（SISH）同时检测HER2蛋白和基因改变，可识别有无基因扩增的HER2阳性乳腺癌。
PLoS One. 2014 Aug 25;9(8):e105961. doi: 10.1371/journal.pone.0105961. eCollection 2014.
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Assessment of HER2 status in breast cancer: overall positivity rate and accuracy by fluorescence in situ hybridization and immunohistochemistry in a single institution over 12 years: a quality control study.乳腺癌中HER2状态的评估：12年间单机构通过荧光原位杂交和免疫组织化学检测的总体阳性率及准确性：一项质量控制研究
BMC Cancer. 2013 Dec 30;13:615. doi: 10.1186/1471-2407-13-615.
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Multiple protein analysis of formalin-fixed and paraffin-embedded tissue samples with reverse phase protein arrays.采用反相蛋白芯片对福尔马林固定石蜡包埋组织样本进行多种蛋白质分析。
Mol Cell Proteomics. 2013 Sep;12(9):2615-22. doi: 10.1074/mcp.M112.023051. Epub 2013 May 7.
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Optical fiber-based in vivo quantification of growth factor receptors.基于光纤的活体生长因子受体定量检测。
Cancer. 2012 Apr 15;118(8):2148-56. doi: 10.1002/cncr.26487. Epub 2011 Aug 25.
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Integrating molecular diagnostics into anticancer drug discovery.将分子诊断学纳入抗癌药物研发。
Nat Rev Drug Discov. 2010 Jul;9(7):523-35. doi: 10.1038/nrd3135. Epub 2010 Jun 7.
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Molecular mechanisms of antigen retrieval: antigen retrieval reverses steric interference caused by formalin-induced cross-links.抗原修复的分子机制：抗原修复可逆转福尔马林诱导的交联所造成的空间位阻。
Biotech Histochem. 2009 Oct;84(5):207-15. doi: 10.3109/10520290903039078.
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Analysis of HER2 gene amplification using an automated fluorescence in situ hybridization signal enumeration system.使用自动荧光原位杂交信号计数系统分析HER2基因扩增
J Mol Diagn. 2007 Apr;9(2):144-50. doi: 10.2353/jmoldx.2007.060102.