Kenunen O G, Prakh'e I V, Kozlovskié V L
Bekhterev Psychoneurological Research Institute, St.-Petersburg.
Zh Vyssh Nerv Deiat Im I P Pavlova. 2001 Sep-Oct;51(5):626-30.
The influence of forced swimming on the development of stress-induced analgesia was studied in 35 SHR mice, 65 NMRI mice, and 23 white outbred male rats. Mice were subjected to swimming conditions (at a temperature of 11 degrees C) for a period of 4 minutes and rats for 6 minutes. Pain thresholds were measured by a footshock. It was shown that behavioral response to acute stress is associated with a change in the pain tolerance threshold: activity of an animal under test conditions positively correlated with stress-induced analgesia. The response to stress and parameters of stress-induced analgesia depend on the genetic factor and age, however, the correlation between the activity during exposure to stress and the extent of stress-induced analgesia conserves in all cases.
在35只自发性高血压大鼠（SHR）、65只NMRI小鼠和23只白化远交雄性大鼠中研究了强迫游泳对应激诱导镇痛作用发展的影响。小鼠在11摄氏度的温度下进行4分钟的游泳，大鼠进行6分钟的游泳。通过足部电击测量疼痛阈值。结果表明，对急性应激的行为反应与疼痛耐受阈值的变化有关：受试动物在测试条件下的活动与应激诱导的镇痛呈正相关。对应激的反应和应激诱导镇痛的参数取决于遗传因素和年龄，然而，在所有情况下，应激暴露期间的活动与应激诱导镇痛程度之间的相关性均保持不变。
