Tondo L, Ghiani C, Albert M
Department of Psychology, University of Cagliari, Sardinia, Italy.
J Clin Psychiatry. 2001;62 Suppl 25:51-5.
Suicide rates vary by country and by mental disorder. What does not vary, though, is that the number of suicides per year is not declining and that a person with a mental disorder is more likely to commit suicide than one without such an illness. Although many pharmacologic interventions have been reported to reduce the risk of suicide among mentally ill patients, especially those with bipolar disorder, the effects of such interventions are inconsistent at best. Lithium is the only medication for which the evidence consistently shows an antisuicidal effect.
自杀率因国家和精神障碍类型而异。然而，不变的是每年的自杀人数并未下降，而且患有精神障碍的人比没有这种疾病的人更有可能自杀。尽管有许多药物干预措施据报道可降低精神病患者尤其是双相情感障碍患者的自杀风险，但这些干预措施的效果充其量也不一致。锂盐是唯一有证据始终显示出抗自杀作用的药物。
