Faccini M, Zuccon W, Caputo P, Gavezzoli D, Manelli A, Bonandrini L
Cattedra di Chirurgia d'Urgenza e Pronto Soccorso Seconda Divisione di Chirurgia d'Urgenza e Pronto Soccorso Istituto Policlinico San Donato, Università degli Studi di Pavia.
Ann Ital Chir. 2001 May-Jun;72(3):337-9; discussion 340.
Following a review of international literature, AA report main results and refer their opinion about the correlation of hemorrhoidal disease with constipation, considering some variants as well as age, sex, breed, social-economic condition and geographic distribution in USA, England and Wales. Epidemiologically ten millions of people, in USA, are affected by hemorrhoidal disease; the incidence rate is 4.4% with an age distribution that shows a prevalence between 45-65 years old subject while constipation has an exponential increase with aging. Hemorrhoidal disease is significantly influenced by sex and geographic distribution that is in white breed more than in black, in social high class and in men more than women. In black breed constipation and hemorrhoidal disease present especially in lower social classes. Based on these results hemorrhoidal disease shows on epidemiological pattern that differ from constipation's one. Many questions are still present about correlations between hemorrhoidal disease and chronic constipation regarding etiopathogenesis. Only future case-control studies will solve the problem.
在对国际文献进行综述之后，AA报告了主要结果，并阐述了他们对于痔病与便秘相关性的看法，同时考虑了一些变量，以及美国、英格兰和威尔士的年龄、性别、品种、社会经济状况和地理分布情况。从流行病学角度来看，美国有1000万人受痔病影响；发病率为4.4%，年龄分布显示45至65岁人群患病率较高，而便秘则随年龄呈指数增长。痔病受性别和地理分布的显著影响，白种人比黑种人更易患病，社会阶层较高者以及男性比女性更易患病。在黑种人中，便秘和痔病尤其多见于社会阶层较低者。基于这些结果，痔病呈现出与便秘不同的流行病学模式。关于痔病与慢性便秘在病因发病机制方面的相关性，仍存在许多问题。只有未来的病例对照研究才能解决这个问题。
