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2型神经纤维瘤病放射治疗后使用听觉脑干植入物恢复听力

Hearing restoration with auditory brainstem implants after radiosurgery for neurofibromatosis type 2.

作者信息

Kalamarides M, Grayeli A B, Bouccara D, Dahan E A, Sollmann W P, Sterkers O, Rey A

机构信息

Department of Neurosurgery and Otolaryngology, Hôpital Beaujon, Faculté Xavier Bichat, Université Paris 7, France.

出版信息

J Neurosurg. 2001 Dec;95(6):1028-33. doi: 10.3171/jns.2001.95.6.1028.

DOI:10.3171/jns.2001.95.6.1028
PMID:11765818
Abstract

The auditory brainstem implant (ABI) is designed to restore useful auditory sensations in patients with neurofibromatosis Type 2 (NF2). The implantation is usually performed at the time of tumor removal in patients who do not undergo radiation treatment. The authors evaluated the performance of ABIs in three patients with NF2 in whom vestibular schwannoma continued to grow after radiation treatment. These three patients with NF2 received a 21-channel ABI; a translabyrinthine approach was used for both the tumor removal and the ABI placement. The interval between radiosurgery and the tumor removal plus device implantation ranged from 2 to 11 years. In all cases, the tumor was growing and the patients presented with total deafness. The mean number of active electrodes in these three patients was equivalent to the average results reported in other patients who received ABIs. The patients in this study used the ABI regularly for everyday life and obtained useful levels of environmental sound recognition. It is concluded that hearing function can be rehabilitated using ABIs in patients with NF2, even if radiosurgery fails to control the tumor growth.

摘要

听觉脑干植入物(ABI)旨在恢复2型神经纤维瘤病(NF2)患者的有用听觉感受。对于不接受放射治疗的患者,植入手术通常在切除肿瘤时进行。作者评估了3例NF2患者的ABI性能,这些患者在放射治疗后前庭神经鞘瘤仍继续生长。这3例NF2患者接受了21通道ABI;采用经迷路入路进行肿瘤切除和ABI植入。放射外科手术与肿瘤切除加装置植入之间的间隔时间为2至11年。在所有病例中,肿瘤都在生长,患者均表现为全聋。这3例患者的平均有效电极数量与其他接受ABI患者的平均结果相当。本研究中的患者在日常生活中定期使用ABI,并获得了有用的环境声音识别水平。得出的结论是,即使放射外科手术未能控制肿瘤生长,使用ABI也可以使NF2患者的听力功能得到恢复。

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Chin Med J (Engl). 2015 May 20;128(10):1363-9. doi: 10.4103/0366-6999.156783.
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[Present state of cochlear implant treatment in adults and children].[成人及儿童人工耳蜗植入治疗的现状]
HNO. 2009 Jul;57(7):693-706. doi: 10.1007/s00106-009-1959-3.
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Clinical experience with gamma knife stereotactic radiosurgery in the management of vestibular schwannomas secondary to type 2 neurofibromatosis.
伽玛刀立体定向放射外科治疗2型神经纤维瘤病继发前庭神经鞘瘤的临床经验。
J Neurol Neurosurg Psychiatry. 2003 Sep;74(9):1288-93. doi: 10.1136/jnnp.74.9.1288.