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多结节性良性甲状腺肿全甲状腺切除术的适应症、风险及接受度

Indications, risks, and acceptance of total thyroidectomy for multinodular benign goiter.

作者信息

Müller P E, Kabus S, Robens E, Spelsberg F

机构信息

Department of Orthopaedics and Orthopaedic Surgery, Universitätsklinikum Rostock, Germany

出版信息

Surg Today. 2001;31(11):958-62. doi: 10.1007/s005950170002.

Abstract

Selective morphology- and function-adapted resection is generally regarded as the surgical treatment of choice for benign goiter causing iodine deficiency. This procedure aims to reduce the need for patients to undergo reoperations for recurrence by completely removing all nodules. However, to achieve this sometimes requires a total thyroidectomy, the option of which is often rejected because of a presumed higher rate of complications. In this study, 324 patients who underwent total thyroidectomy were evaluated retrospectively. The patients were interviewed about their postoperative course and their acceptance of the procedure performed. The complications were compared with those associated with subtotal resection or hemithyroidectomies performed in our collective experience. The rate of complications associated with total thyroidectomy, namely, recurrent nerve palsy in 0.9%, hypocalcemia in 0.9%, wound infection in 0.9%, and secondary hemorrhage in 0.6%, did not differ significantly from that associated with subtotal resections/ hemithyroidectomies. Moreover, 88.3% of the patients who underwent total thyroidectomy were satisfied with the results of surgery. These findings indicate that total thyroidectomy is an acceptable surgical alternative for benign multinodular goiters.

摘要

选择性形态和功能适应性切除术通常被视为治疗因碘缺乏引起的良性甲状腺肿的首选手术方法。该手术旨在通过完全切除所有结节来减少患者因复发而再次手术的必要性。然而,有时要做到这一点需要进行全甲状腺切除术,而由于推测其并发症发生率较高,这种选择往往被拒绝。在本研究中,对324例行全甲状腺切除术的患者进行了回顾性评估。对患者进行了术后病程及对所施行手术接受程度的访谈。将这些并发症与我们积累的经验中与次全切除术或半甲状腺切除术相关的并发症进行了比较。全甲状腺切除术相关的并发症发生率,即喉返神经麻痹为0.9%,低钙血症为0.9%,伤口感染为0.9%,继发性出血为0.6%,与次全切除术/半甲状腺切除术相关的并发症发生率相比无显著差异。此外,88.3%接受全甲状腺切除术的患者对手术结果感到满意。这些发现表明,全甲状腺切除术是治疗良性多结节性甲状腺肿可接受的手术选择。

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