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[The role of hyperlactatedehydrogenasemia in induction of metabolic disorders in the body].

作者信息

Gil'miiarova F N, Radomskaia V M, Baisheva G M, Kretova I G, Kleĭman M S, Pervova Iu V

机构信息

Department of Fundamental and Clinical Biochemistry with Laboratory Diagnostic of Samara State Medical University.

出版信息

Vopr Med Khim. 2001 Sep-Oct;47(5):469-76.

Abstract

The effect of intravenous administration of lactate dehydrogenase (5000 E/kg) on some metabolic parameters was investigated. The hyperenzymemia was accompanied by changes of metabolite content (glutamate, 2-oxoglutarate, lactate, dihydroxyacetone phosphate) and enzyme activities (aldolase, lactate dehydrogenase, transaminase) in heart, liver and skeletal muscles. Intravenously administered tritiated lactate dehydrogenase was preferentially found in skeletal muscles, liver, kidneys and some other organs.

摘要

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