Purification and characterization of a kininase from human urine.

A kininase has been purified from male human urine which splits the C-terminal arginyl residue from bradykinin, but does not split hippuryl-L-arginine or converts Angiotensin I into Angiotensin II. It contains cadmium ion in its active center, and has a molecular weight of 210,000 by ultracentrifugation.