[Dose and adequacy of hemodialysis measured by the urea reduction ratio (URR and Kt/V)].

BACKGROUND

There are little reports about prescribed and delivered dose of haemodialysis (HD) in B&H. If we want to reduce acute and chronic HD complications and to improve whole result of patients treatment, it is necessary to routinely monitoring and measurement of delivered dose of HD. Prescribed and delivered dose of HD have to be equal or near equal.

METHODS

Blood samples were taken after the long interval in a thrice-weekly regimen before and 10 min after ultrafiltration, using Slow Flow/Stop Pumping. We measured delivered and prescribed dose of HD by URR and Kt/V, and efficacy of HD by QE. The results were processing by computerized urea kinetic modelling program.

RESULTS

The mean URR was 64.69%. Mean prescribed Kt/V was 1.25 +/- 0.16 and delivered 1.23 +/- 0.14, and QE 0.99 +/- 15. Delivered Kt/V and QE were positively associated (p < 0.001). QE was significantly associated with post HD urea, and sex, but not with treatment time.

CONCLUSIONS

We suggest that Kt/V can serve as an important parameter in the dose of HD, and QE as a measure of dialysis "efficacy" in a single treatment of an individual patient.