Jiang T, Wu X, Jia C
Departmen of Cardiology, Beijing Anzhen Hospital, Beijing 100029, China.
Zhonghua Nei Ke Za Zhi. 2001 Oct;40(10):663-5.
To evaluate the immediate and follow-up results of percutaneous transluminal septal myocardial ablation (PTSMA) in patients with hypertrophic obstructive cardiomyopathy (HOCM).
15 patients with HOCM refractory to medication successfully underwent PTSMA under myocardial contrast echocardiography.
The left ventricular outflow gradients (LVOTG) were reduced significantly (77.93 +/- 22.00) mm Hg to (14.8 +/- 15.0) mm Hg (P < 0.0001) immediately with a mean decrease of (5.75 +/- 2.87) mm Hg (P < 0.001) in left ventricular end diastolic pressure. The scores of SAM and mitral regurgition During a mean of 8.6 +/- 3.8(6-22) months follow-up, the patients heart function (NYHA) were greatly improved(3.4 +/- 0.5 vs 1.1 +/- 0.4, P < 0.001), and disappearance of angina pectoris, and exercise endurance improvement with steady hemodynamic improvement.
PTSMA is effectively non-surgical treatment method for drug-refractory patients with HOCM.
评估经皮腔内室间隔心肌消融术（PTSMA）治疗肥厚性梗阻性心肌病（HOCM）患者的即刻及随访结果。
15例药物治疗无效的HOCM患者在心肌对比超声心动图引导下成功接受了PTSMA治疗。
左心室流出道压差（LVOTG）即刻显著降低，从（77.93±22.00）mmHg降至（14.8±15.0）mmHg（P<0.0001），左心室舒张末期压力平均下降（5.75±2.87）mmHg（P<0.001）。在平均8.6±3.8（6 - 22）个月的随访期间，患者的心脏功能（纽约心脏协会心功能分级）显著改善（3.4±0.5对1.1±0.4，P<0.001），心绞痛消失，运动耐力提高，血流动力学持续改善。
PTSMA是治疗药物难治性HOCM患者的一种有效的非手术治疗方法。
