[Changes of pulmonary function and partial oxygen pressure before and after bronchoalveolar lavage in patients with interstitial lung diseases].

OBJECTIVE

To study the influence of bronchoalveolar lavage(BAL) on pulmonary physiological function and partial oxygen pressure(PaO2).

METHODS

Pulmonary function and partial oxygen pressure were measured in 42 patients with interstitial lung disease (ILD) before and after BAL, 7 non-smoker volunteers as control group.

RESULTS

VC% and FEV1% decreased significantly from (74 +/- 17)% to (64 +/- 19)% and from (72 +/- 9)% to (65 +/- 12)%, respectively. PaO2 decreased from(77 +/- 11) mm Hg to (63 +/- 11) mm Hg. The above parameters were also decreased in control group, but had no statistical significance.

CONCLUSION

Pulmonary physiological function and partial oxygen pressure of patients with ILD are influenced by BAL process.