Dietze G, Wicklmayr M, Czempiel H, Henftling H G, Hepp K D, Mehnert H
Klin Wochenschr. 1975 Jul 1;53(13):639-40. doi: 10.1007/BF01469686.
After the inhalation of 133xenon continuous registrations of portal 133xenon concentrations showed that the monoexponential terminal component of the hepatic-venous 133xenon-clearance might be due to the recirculation of the gas from the gut. Accordingly, in all the cases, with the application of the wellknown "extrapolation and peeling off" of this monoexponential terminal component from this part of the hepatic-venous 133xenon-clearance, not affected any more by arterial recirculation a monoexponential 133xenon-clearance could be separated. The time-constant of the latter was similar to that of the well-knwon specific hepatic 133xenon-clearance after the application of the gas by injection into the portal vein.
吸入133氙后,对门静脉133氙浓度进行连续记录,结果显示肝静脉133氙清除率的单指数终末成分可能是由于气体从肠道再循环所致。因此,在所有病例中,通过对肝静脉133氙清除率的这一部分应用众所周知的单指数终末成分“外推和剥离”方法,不再受动脉再循环影响后,可以分离出单指数133氙清除率。后者的时间常数与经门静脉注射气体后众所周知的特异性肝133氙清除率的时间常数相似。