Owens Jonathan M, Gomez Jose A, Byers Robert M
Baylor College of Medicine, Houston, Texas.
Head Neck. 2002 Jan;24(1):91-4. doi: 10.1002/hed.1155.
Malignant mucosal melanoma of the head and neck is a rare cancer in adults that carries a grave prognosis. Three mucosal melanomas in pediatric patients have previously been reported.
We present here the youngest case of malignant mucosal melanoma of the head and neck in a 3-month-old boy. He presented with a 2 x 2-mm-pigmented lesion on the anterior maxillary alveolus. The patient was treated with local excision alone.
The patient has remained disease free with regular follow-up for 117 months.
Based upon this case and the few cases reported in the literature, mucosal melanoma is a much less common disease in children than in adults. Further, juvenile mucosal melanoma displays a benign clinical behavior.
头颈部恶性黏膜黑色素瘤是成人中的一种罕见癌症,预后严重。此前已报道过3例儿科患者的黏膜黑色素瘤。
我们在此报告一名3个月大男童,他是头颈部恶性黏膜黑色素瘤最年轻的病例。他上颌前牙槽出现一个2×2毫米的色素沉着病变。该患者仅接受了局部切除治疗。
患者经过117个月的定期随访,一直无病生存。
基于该病例及文献中报道的少数病例,黏膜黑色素瘤在儿童中比在成人中少见得多。此外,青少年黏膜黑色素瘤表现出良性的临床行为。