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[抗肿瘤卡介苗治疗的一种罕见并发症:肺结核]

[A rare complication of antineoplastic BCG therapy: pulmonary tuberculosis].

作者信息

Fenniche S, Hasséne H, Attia S, Fkih L, Bousnina S, Cheikh K, Belhabib D, Megdiche M L

机构信息

Service Ibn Nafiss, Hôpital A. Mami Ariana, Tunisie.

出版信息

Tunis Med. 2001 Aug-Sep;79(8-9):467-70.

Abstract

Local treatment with intra vesical BCG for bladder carcinoma have few complications. Pulmonary side effects are rare, like interstitial pneumonitis. We report a case of a 77-year-old man, treated with BCG for bladder carcinoma who developed illness and tumoral chest-X-ray opacity. Mycobacterium tuberculosis bovis was isolated in culture and 2 years after in sputum. Physio pathologic mechanism of pulmonary features remains controversial, however this case suggest that lung lesions can be result of an infection process.

摘要

膀胱内灌注卡介苗治疗膀胱癌的局部治疗并发症较少。肺部副作用罕见,如间质性肺炎。我们报告一例77岁男性,因膀胱癌接受卡介苗治疗后出现疾病和胸部X线片上的肿瘤性阴影。培养物中分离出牛分枝杆菌,两年后痰液中也分离出该菌。肺部特征的生理病理机制仍存在争议,然而该病例表明肺部病变可能是感染过程的结果。

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