Peng Z, Pan X, Liu H
Department of Obstetrics and Gynecology, Second Affiliated Hospital, West China University of Medical Sciences, Chengdu 610041.
Zhonghua Zhong Liu Za Zhi. 1999 Mar;21(2):142-4.
To investigate the value and feasibility of surgical excision of gastro-intestinal metastatic tumors in patients with ovarian malignancy.
The surgical and clinical data were retrospectively reviewed in 131 cases of ovarian malignant tumor with surgically excised gastrointestinal metastasis (> or = 2 cm in diameter).
Ovarian malignant tumor with gastro-intestinal metastasis accounted for 28.9% of the patients with primary ovarian malignancies in the same time period. Of the 131 cases, 126(93.9%) were in stage III and IV. The treatment was surgical excision combined with chemotherapy. Of the 141 operations, 83 (58.9%) were done by stripping of tumors on the gastro-intestinal wall and repair, 31(22.0%) received resection of the involved segment of the bowel with anastomosis, 27(19.2%) with colostomies. Postoperative complications occurred in 26.9% of the operated patients. The overall 2- and 5-year survival rate was 79.7% and 42.5%, respectively.
Surgical excision of gastro-intestinal tumors metastasized from primary ovarion malignancies is feasible to achieve cytoreduction. Prognosis can be improved when combined with chemotherapy.
探讨手术切除卵巢恶性肿瘤患者胃肠道转移瘤的价值及可行性。
回顾性分析131例手术切除直径≥2 cm胃肠道转移灶的卵巢恶性肿瘤患者的手术及临床资料。
卵巢恶性肿瘤合并胃肠道转移瘤患者占同期原发性卵巢恶性肿瘤患者的28.9%。131例中，126例（93.9%）为Ⅲ期和Ⅳ期。治疗方法为手术切除联合化疗。141例手术中，83例（58.9%）行胃肠道壁肿瘤剥除及修补术，31例（22.0%）行受累肠段切除吻合术，27例（19.2%）行结肠造口术。术后并发症发生率为26.9%。总体2年和5年生存率分别为79.7%和42.5%。
手术切除原发性卵巢恶性肿瘤转移至胃肠道的肿瘤以实现肿瘤细胞减灭是可行的。联合化疗可改善预后。
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