Baba T, Tani T
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama.
Yakushigaku Zasshi. 2001;36(1):10-7.
Two kinds of creosote have been found based on historical evidence of the medicinal uses and origins. One is wood creosote, and distillate of wood-tar containing guaiacol and creosol. The other type of creosote is coal-tar creosote, obtained from coal-tar, containing naphthalene and anthracene as the major constituents. Wood creosote was prepared for the first time in Germany in 1830 and was used for medicinal purposes. It had been listed officially in the German, American, and Japanese Pharmacopoeia as an antibacterial agent for the treatment of pulmonary tuberculosis, diarrhea, and external injury. In recent days, it has been deleted from the Pharmacopoeia in Western countries and not officially used for medicinal purposes. However, wood creosote is still been listed in the Japanese Pharmacopoeia and is used for the treatment of diarrhea. Since the interest of common people in herbal medicines and self-medication has been increasing, the use of wood creosote has also been modified in combination with some herbal drugs, "Seiro-gan" especially is quite popular in Japan as a self-medication for digestive trouble, including food poisoning or diarrhea.
根据药用用途和来源的历史证据，已发现两种杂酚油。一种是木杂酚油，是含有愈创木酚和甲酚的木焦油馏出物。另一种杂酚油是煤焦油杂酚油，从煤焦油中获得，主要成分是萘和蒽。木杂酚油于1830年在德国首次制备并用于医药用途。它曾被正式列入德国、美国和日本药典，作为治疗肺结核、腹泻和外伤的抗菌剂。近年来，它已从西方国家的药典中删除，不再正式用于医药用途。然而，木杂酚油仍被列入日本药典，并用于治疗腹泻。由于普通民众对草药和自我药疗的兴趣不断增加，木杂酚油也与一些草药联合使用，尤其是“清老丸”在日本作为治疗包括食物中毒或腹泻在内的消化问题的自我药疗药物相当受欢迎。
