Van Bogaert A, De Schepper J, Mees U
Arch Mal Coeur Vaiss. 1979 Jul;72(7):721-9.
Electrical stimulation in the area around the ventro-median nuclei of the hypothalamus of the dog produced changes suggestive of ischaemia in the standard bipolar and epicardial leads, principally over the apical, lateral and diaphragmatic walls of the left ventricle. It is suggested that these changes may be the central expression of orthosympathetic stimulation by released catecholamines on the permeability and membrane potentials of the myocardial cells with respect to ions, especially Ca++.
对狗下丘脑腹内侧核周围区域进行电刺激，在标准双极导联和心外膜导联中产生了提示缺血的变化，主要出现在左心室的心尖、侧壁和膈面。有人认为，这些变化可能是释放的儿茶酚胺对心肌细胞离子（尤其是Ca++）通透性和膜电位进行交感神经刺激的中枢表现。
