[成纤维细胞与伤口修复的研究进展]
[Research progress of fibroblast and wound repair].
作者信息
Wang Y, Wei F, Liu M
机构信息
Department of Pediatric Surgery, First University Hospital, West China University of Medical Sciences, Chengdu Sichuan, P. R. China 610041.
出版信息
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2000 Mar;14(2):126-8.
OBJECTIVE
To review the recent advances in fibroblast study and its role in wound repair.
METHODS
Recent original articles related to wound repair were retrieved extensively, and the effect of fibroblast on every stages of repair were summed up and comprehended.
RESULTS
Fibroblast plays important roles in granulation formation, wound contraction, matrix synthesis, wound repair, scar formation and scarless repair by means of growth factors modulation.
CONCLUSION
The understanding of fibroblast in the wound repair can promote the progress of biological therapy of wound repair and scar prevention.
目的
综述成纤维细胞研究的最新进展及其在伤口修复中的作用。
方法
广泛检索近期与伤口修复相关的原创文章，总结并理解成纤维细胞在修复各阶段的作用。
结果
成纤维细胞通过调节生长因子在肉芽形成、伤口收缩、基质合成、伤口修复、瘢痕形成和无瘢痕修复中发挥重要作用。
结论
对伤口修复中细胞的认识可促进伤口修复生物治疗及瘢痕预防的进展。
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