Zhu L, Niu S, Li S
Institute of Respiratory Disease, Shanghai Medical University, Department of Pulmonology, Zhongshan Hospital, Shanghai 200032, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2000 Apr;23(4):225-7.
To Evaluate the effect of nasal or oranasal face mask mechanical ventilation (FMMV) in the treatment of patients with acute respiratory distress syndrome(ARDS).
16 ARDS patients were separated into two groups: infection group and non-infection group. The former had 6 cases with pneumonia and 1 case with sepsis; the later had 5 cases with multiple fracture, 2 with operation of intestines obstruction, 1 with operation of spleen rupture, 1 with hepatectomy. In Infection group, the respiratory rate(RR) was (46 +/- 5) times/min, the arterial blood pH 7.49 +/- 0.05, CO2 partial pressure(PaCO2) was (32 +/- 4) mm Hg, and oxygenation index (OI) (144 +/- 23) mm Hg. In non-infection group, the RR, pH, PaCO2, OI was (41 +/- 6) times/min, 7.49 +/- 0.13, (32 +/- 5) mm Hg, (156 +/- 51) mm Hg. All patients were linked with ventilator via nasal or ornasal mask. Pressure support ventilation (PSV) and positive end-expiratory pressure (PEEP) were selected.
All patients successfully received FMMV. In infection group, RR and OI returned to (45 +/- 7) times/min (P > 0.05) and (195 +/- 30) mm Hg(P < 0.05) respectively after 2-8 hours via FMMV. But in non-infection group, the RR and OI were (35 +/- 4) times/min (P < 0.05) and (228 +/- 90) mm Hg(P < 0.05). 2 cases(29%) in infection group and 8 cases(89%) in non-infection were successfully weaned from FMMV.
FMMV could be as the first choice in ARDS patients without infection, and airway intubation should be given in infectious patients as early as possible.