Phillips William D, Froehner Stanley C
Department of Physiology, University of Sydney, NSW 2006, Australia.
Neuron. 2002 Jan 3;33(1):4-6. doi: 10.1016/s0896-6273(01)00569-4.
Coyle et al. (2002), in this issue of Neuron, reveal the crystal structure for the GABA(A) receptor binding protein, GABARAP. They show GABARAP can switch from a monomer to an extended linear polymer form that may function to assemble microtubules during the intracellular trafficking or postsynaptic clustering of GABA(A) receptors.
科伊尔等人（2002年）在本期《神经元》杂志上公布了γ-氨基丁酸A（GABA(A)）受体结合蛋白GABARAP的晶体结构。他们发现，GABARAP能从单体转变为一种延伸的线性聚合物形式，这种形式可能在GABA(A)受体的细胞内运输或突触后聚集过程中发挥作用，用于组装微管。
