Masala S, Fanucci E, Ronconi P, Sodani G, Taormina P, Romagnoli A, Simonetti G
Dipartimento di Diagnostica per Immagini e Radiologia Interventistica, Università degli Studi Tor Vergata, Rome, Italy.
Radiol Med. 2001 Nov-Dec;102(5-6):370-3.
The cause of intermetatarsal neuromas is unclear; the pathogenesis is, most likely, a mechanically induced degenerative neuropathy or an entrapment of the intermetatarsal nerve under the transverse intermetatarsal ligament. Treatment of intermetatarsal neuromas includes very simple methods, such as changing shoe styles, or more complex conservative treatments such as orthotic devices and steroid injections until surgical therapy. This study aimed to evaluate the neuroma's intralesional treatment with alcohol sclerosing injection as a viable alternative to steroid injections or surgery in persisting symptoms.
23 patients with clinical symptoms of intermetatarsal neuroma and who had not undergone other treatments were treated with 30% alcohol applied under US guide. Each patient received from 3 to 7 applications at 7 to 10 day intervals.
We performed 3 applications in 17 patients, 5 in 5 patients and 7 in 1 patient for a total of 83 applications with a technical success of 100%. A complete resolution of all symptoms was achieved in 91% of the patients.
Alcohol sclerosing intralesional treatment under US guide is a viable alternative to conservative or surgery treatments in patients with intermetatarsal neuromas.
跖间神经瘤的病因尚不清楚；其发病机制很可能是机械性诱发的退行性神经病变或跖间神经在跖间横韧带下受压。跖间神经瘤的治疗方法包括非常简单的措施，如更换鞋型，或更复杂的保守治疗，如使用矫形器械和注射类固醇，直至采取手术治疗。本研究旨在评估用酒精硬化注射进行瘤内治疗，作为类固醇注射或手术治疗后症状持续存在时的一种可行替代方法。
23例有跖间神经瘤临床症状且未接受过其他治疗的患者，在美国超声引导下注射30%酒精进行治疗。每位患者每隔7至10天接受3至7次注射。
17例患者接受3次注射，5例患者接受5次注射，1例患者接受7次注射，共进行83次注射，技术成功率为100%。91%的患者所有症状完全消失。
在美国超声引导下进行酒精硬化瘤内治疗，对于患有跖间神经瘤的患者来说，是保守治疗或手术治疗的一种可行替代方法。
