[经阴道超声检查与子宫内膜细胞学检查联合用于绝经后妇女子宫内膜疾病的诊断]

[Combining transvaginal sonography and endometrial cytology in the diagnosis of endometrial disorders in postmenopausal women].

作者信息

Sheng J, Chen Y, Pan J

机构信息

Department of Gynecology, Beijing Obstetric and Gynecology Hospital, Affiliated to Medical Science of Capital University, Beijing 100006, China.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 2001 Jun;36(6):341-3.

PMID:11783131

Abstract

OBJECTIVE

To evaluate the combined use of transvaginal sonography and endometrial cytology for the diagnosis of endometrial disorders in postmenopausal women.

METHODS

One hundred forty-three patients with postmenopausal uterine bleeding were studied prospectively. Transvaginal sonography was used to measure the endometrial thickness (double layers), followed by use of the ori endometrial sampler. The results were compared to the histopathologic diagnosis of specimens obtained by dilatation and curettage.

RESULTS

When the cutoff point of endometrial thickness was set at 5 mm to detect endometrial malignancy and premalignancy, transvaginal sonography showed a 100.0% sensitivity and 56.9% false positive rate. Endometrial cytology showed a 96.3% specificity but it had a 2.5% false negative rate. The combined use of transvaginal sonography and endometrial cytology can decrease false positive rate of transvaginal sonography from 56.9% to 43.2% (P < 0.01).

CONCLUSION

The combined use of transvaginal sonography and endometrial cytology is a good method to screen endometrial malignancy and premalignancy.

摘要

目的

评估经阴道超声检查与子宫内膜细胞学检查联合应用于绝经后女性子宫内膜疾病诊断的效果。

方法

前瞻性研究143例绝经后子宫出血患者。采用经阴道超声检查测量子宫内膜厚度（双层），随后使用ori子宫内膜取样器。将结果与通过刮宫术获取的标本的组织病理学诊断结果进行比较。

结果

当将子宫内膜厚度的截断点设定为5mm以检测子宫内膜恶性病变和癌前病变时，经阴道超声检查的灵敏度为100.0%，假阳性率为56.9%。子宫内膜细胞学检查的特异性为96.3%，但假阴性率为2.5%。经阴道超声检查与子宫内膜细胞学检查联合应用可将经阴道超声检查的假阳性率从56.9%降至43.2%（P<0.01）。