[痉挛与多发性硬化症]
[Spasticity and multiple sclerosis].
作者信息
Bussel B, Neris O R, Mailhan L
机构信息
Service de rééducation neurologique, Hôpital R. Poincaré, 92380 Garches.
出版信息
Rev Neurol (Paris). 2001 Sep;157(8-9 Pt 2):1041-4.
Spasticity is a common symptom in MS patients. It is easy to recognize and evaluate spasticity at rest. The efficacy of numerous treatments has been well documented. Nevertheless, it is difficult, particularly in MS patients, to assess the functional disability due to spasticity and the functional benefit due to treatment. This is why it is appears more appropriate to use therapeutic tests with transitory effects such as anesthetic blocks in case of focal spasticity or intrathetical baclofen in case of diffuse spasticity. It is also possible to use reversible treatments such as botulinum toxin injections before proposing section of a peripheral nerve.
痉挛是多发性硬化症患者的常见症状。静止时的痉挛很容易识别和评估。许多治疗方法的疗效已有充分记录。然而，尤其是在多发性硬化症患者中，评估痉挛导致的功能障碍以及治疗带来的功能益处是困难的。这就是为什么在局灶性痉挛的情况下使用具有短暂效果的治疗性试验（如麻醉阻滞）或在弥漫性痉挛的情况下使用鞘内注射巴氯芬似乎更为合适。在建议切断周围神经之前，也可以使用肉毒杆菌毒素注射等可逆性治疗方法。
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