Congreve Miles S, Jamieson Craig
Astex Technology, 250 Cambridge Science Park, Milton Road, Cambridge, UK CB4 0WE.
Drug Discov Today. 2002 Jan 15;7(2):139-42. doi: 10.1016/s1359-6446(01)02094-3.
This review describes recent developments in approaches to high-throughput reaction optimization, as well as the associated analytical techniques. The studies discussed include the use of UV-visible, IR-thermographic and mass spectrometric methods for application in catalyst development, process optimization and materials science. Other methods of potential use in a high-throughput format are also discussed.
本综述描述了高通量反应优化方法以及相关分析技术的最新进展。所讨论的研究包括将紫外可见、红外热成像和质谱方法应用于催化剂开发、工艺优化和材料科学。还讨论了其他可能以高通量形式使用的方法。