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[肌酸及其他可磷酸化氨基酸化合物对大鼠回肠钙-45吸收的影响]

[Effect of creatine and other phosphorylable amino compounds on the ileal absorption of Ca-45 in the rat].

作者信息

Tardivel S, Dupuis Y, Fournier P

出版信息

C R Seances Acad Sci D. 1979 Jul 9;289(2):113-6.

PMID:117913
Abstract

Some carbohydrates which increase calcium absorption were phosphate acceptors. When administrated to adult Rat in ileal ligated loop, phosphorylable amino compounds such as creatine, L-aspartic and L-glutamic acids also increased calcium absorption; other effective compounds such as D- and L-lysine and D-alanine might be involved in reactions of phorphorylation. L-alanine, L- and D-valine and asparagine were ineffective in enhancing calcium absorption and were not phosphorylable. Injection of creatine into ileal loop induced the formation of its phosphorylated derivative. Absorption of the amino compound was not correlated with the fact that they were effective on calcium absorption.

摘要

一些可增加钙吸收的碳水化合物是磷酸盐受体。当在成年大鼠的回肠结扎肠袢中给予时,可磷酸化的氨基化合物,如肌酸、L-天冬氨酸和L-谷氨酸,也能增加钙吸收;其他有效化合物,如D-和L-赖氨酸以及D-丙氨酸,可能参与磷酸化反应。L-丙氨酸、L-和D-缬氨酸以及天冬酰胺在增强钙吸收方面无效,且不可磷酸化。将肌酸注入回肠肠袢会诱导其磷酸化衍生物的形成。氨基化合物的吸收与它们对钙吸收有效这一事实无关。

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