Nitric oxide synthase inhibition decreases output of hepatic insulin sensitizing substance (HISS), which is reversed by SIN-1 but not by nitroprusside.

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作者信息

Guarino M P, Correia N C, Raposo J, Macedo M P

机构信息

Departamento de Fisiologia-FCM-UNL, Campo Mártires da Pátria, 130, 1169-056 Lisboa, Portugal.

出版信息

Proc West Pharmacol Soc. 2001;44:25-6.

PMID:11793984

Abstract

摘要

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相似文献

Nitric oxide synthase inhibition decreases output of hepatic insulin sensitizing substance (HISS), which is reversed by SIN-1 but not by nitroprusside.

Proc West Pharmacol Soc. 2001;44:25-6.

Insulin sensitivity is mediated by the activation of the ACh/NO/cGMP pathway in rat liver.

Am J Physiol Gastrointest Liver Physiol. 2004 Sep;287(3):G527-32. doi: 10.1152/ajpgi.00085.2004.

Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action.

Am J Physiol Gastrointest Liver Physiol. 2003 Apr;284(4):G588-94. doi: 10.1152/ajpgi.00423.2002. Epub 2002 Dec 4.

Blockade of hepatic nitric oxide synthase causes insulin resistance.

Am J Physiol. 1999 Jul;277(1):G101-8. doi: 10.1152/ajpgi.1999.277.1.G101.

Hepatic portal venous delivery of a nitric oxide synthase inhibitor enhances net hepatic glucose uptake.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E768-77. doi: 10.1152/ajpendo.00184.2007. Epub 2008 Jan 22.

Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E300-6. doi: 10.1152/ajpendo.00380.2007. Epub 2007 Nov 20.

Nitric oxide reduces organ injury and enhances regeneration of reduced-size livers by increasing hepatic arterial flow.

Br J Surg. 2008 Jun;95(6):785-92. doi: 10.1002/bjs.6139.

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Proc West Pharmacol Soc. 1997;40:19-20.

Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla.

Comp Biochem Physiol A Mol Integr Physiol. 2007 Oct;148(2):368-73. doi: 10.1016/j.cbpa.2007.05.025. Epub 2007 Jun 7.

Participation of the NO-cyclic GMP pathway in rofecoxib-induced antinociception.

Proc West Pharmacol Soc. 2003;46:165-7.

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Regulation of obesity and insulin resistance by nitric oxide.

Free Radic Biol Med. 2014 Aug;73:383-99. doi: 10.1016/j.freeradbiomed.2014.05.016. Epub 2014 May 28.

Co-administration of glutathione and nitric oxide enhances insulin sensitivity in Wistar rats.

Br J Pharmacol. 2006 Apr;147(8):959-65. doi: 10.1038/sj.bjp.0706691.