Winn H Richard, Jane John A, Taylor James, Kaiser Donald, Britz Gavin W
Department of Neurosurgery, University of Washington, Harborview Medical Center, Seattle 98104, USA.
J Neurosurg. 2002 Jan;96(1):43-9. doi: 10.3171/jns.2002.96.1.0043.
The prevalence of unruptured cerebral aneurysms is unknown, but is estimated to be as high as 5%. The goal of this study was to determine the prevalence of asymptomatic incidental aneurysms.
The authors studied all cerebral arteriography reports produced at a single institution, the University of Virginia, between April 1969 and January 1980. A review of 3684 arteriograms demonstrated 24 cases of asymptomatic aneurysms, yielding a prevalence rate of 0.65%. The majority (67%) of the 24 patients harboring unruptured aneurysms were women. More than 90% of the unruptured aneurysms were located in the anterior circulation and in locations similar to those found in patients with ruptured aneurysms. Nearly 80% of the aneurysms were smaller than 1 cm in their greatest diameter. The frequency of asymmetrical unruptured aneurysms (0.6-1.5%) was constant throughout all relevant age ranges (35-84 years).
While keeping in mind appropriate caveats in extrapolating from these data, the prevalence rate of asymptomatic unruptured aneurysms found in the present study allows an estimation of the yearly rate of rupture of these lesions. The authors suggest that this yearly rate of rupture falls within the range of 1 to 2%.
未破裂脑动脉瘤的患病率尚不清楚,但估计高达5%。本研究的目的是确定无症状偶然发现动脉瘤的患病率。
作者研究了弗吉尼亚大学在1969年4月至1980年1月期间生成的所有脑动脉造影报告。对3684份动脉造影的回顾显示有24例无症状动脉瘤,患病率为0.65%。24例患有未破裂动脉瘤的患者中,大多数(67%)为女性。超过90%的未破裂动脉瘤位于前循环,且位置与破裂动脉瘤患者的位置相似。近80%的动脉瘤最大直径小于1厘米。在所有相关年龄范围(35 - 84岁)内,不对称未破裂动脉瘤的发生率(0.6 - 1.5%)是恒定的。
在从这些数据进行推断时牢记适当的注意事项的同时,本研究中发现的无症状未破裂动脉瘤的患病率有助于估计这些病变的年破裂率。作者认为,这种年破裂率在1%至2%的范围内。