Synthesis and anti-HIV activity of new modified 1,2,3-triazole acyclonucleosides.
作者信息
Lazrek H B, Taourirte M, Oulih T, Barascut J L, Imbach J L, Pannecouque C, Witrouw M, De Clercq E
机构信息
Laboratoire de Chimie Bio-Organique, Faculté des Sciences Semlalia, Marrakech, Maroc.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2001 Dec;20(12):1949-60. doi: 10.1081/NCN-100108325.
PMID:11794800
Abstract
The synthesis of 1,2,3-triazole acyclonucleosides 7a-h via 1,3-dipolar cycloaddition of N-9/N-1-propargylpurine/pyrimidine 2a-h with azido-pseudo-sugar 4 is described and none of them had anti-HIV activity.
摘要
Zotero 插件