Dai Guangxiu, Larock Richard C
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Org Lett. 2002 Jan 24;4(2):193-6. doi: 10.1021/ol010230y.
[reaction: see text] o-(1-Alkynyl)benzaldimines react with aryl iodides and 1 atm of CO in the presence of tri-n-butylamine and a Pd(PPh(3))(4) catalyst to afford good yields of 3-substituted 4-aroylisoquinolines by acylpalladation of the carbon-carbon triple bond and cyclization.
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