Polad J E, Wilson L M
Southampton General Hospital, Southampton, UK.
Heart. 2002 Feb;87(2):E2. doi: 10.1136/heart.87.2.e2.
A 65 year old woman with history of ischaemic heart disease underwent standard adenosine stress test for myocardial perfusion imaging. She sustained inferior myocardial infarction during the final stages of the stress test. She was admitted to the coronary care unit and received thrombolytic treatment. The patient made an uneventful recovery. Adenosine is widely used for myocardial stress imaging tests and has a good safety profile. So far there has been only one other reported myocardial infarction during adenosine stress test, which was under special circumstances because three days before the test the patient had undergone percutaneous transluminal coronary angioplasty when a severe circumferential dissection was noted. The present patient's case highlights the need to be aware of rare but potentially serious complications of adenosine, even though it generally has an excellent safety record for use in myocardial stress testing.
一位有缺血性心脏病史的65岁女性接受了用于心肌灌注成像的标准腺苷负荷试验。她在负荷试验的最后阶段发生了下壁心肌梗死。她被收入冠心病监护病房并接受了溶栓治疗。患者恢复顺利。腺苷广泛用于心肌负荷成像检查,安全性良好。到目前为止,腺苷负荷试验期间仅另有一例心肌梗死的报道,且是在特殊情况下,因为在试验前三天患者接受了经皮冠状动脉腔内血管成形术,术中发现严重的环形夹层。本患者的病例凸显了尽管腺苷在心肌负荷试验中总体安全性良好,但仍需警惕其罕见但可能严重的并发症。