一种新型水溶性N-保护基，2-（苯基（甲基）磺酰基）乙氧基羰基四氟硼酸盐及其在水相固相肽合成中的应用。
A new water-soluble N-protecting group, 2-(phenyl(methyl)sulfonio)ethyloxycarbonyl tetrafluoroborate, and its application to solid phase peptide synthesis in water.
作者信息
Hojo K, Maeda M, Kawasaki K
机构信息
Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Japan.
出版信息
J Pept Sci. 2001 Dec;7(12):615-8. doi: 10.1002/psc.361.
DOI:10.1002/psc.361
PMID:11798017
Abstract
A new water-soluble N-protecting group, 2-[phenyl(methyl)sulfoniolethyloxycarbonyl tetrafluoroborate, has been prepared and its application to solid phase peptide synthesis in water has been studied. Leu-enkephalin amide was successfully synthesized in water by the solid phase method using this protecting group.
摘要
一种新的水溶性N-保护基，2-[苯基（甲基）磺酰基乙氧基羰基四氟硼酸盐，已被制备，并研究了其在水相固相肽合成中的应用。使用该保护基通过固相法在水中成功合成了亮氨酸脑啡肽酰胺。
Zotero 插件