Use of morphine and adjuvant drugs according to the condition.

Adjuvant drugs are used to enhance effects of analgesics and morphine-resistant pain such as neuropathic pain. If morphine provides inadequate pain relief and evokes drowsiness, morphine is usually ineffective. The key is the patient's reaction to morphine. When a patient's pain includes neuropathic pain, a combination of morphine and non-steroidal anti-inflammatory drugs is partially effective, but morphine-resistant pain remains. Increasing morphine dosage causes drowsiness without pain improvement. Appropriate adjuvant drugs are necessary in these conditions.