Creagan E T, Wilkinson J M
Mayo Medical School, Rochester, Minnesota.
Am Fam Physician. 1989 Dec;40(6):133-40.
A systematic approach to identifying the cause of pain and rational use of drug therapy are keys to providing pain relief to cancer patients. Aspirin, acetaminophen and nonsteroidal anti-inflammatory drugs are effective for mild to moderate pain, and they enhance the effectiveness of weak oral narcotics, such as codeine. For severe pain, morphine is the drug of choice. A variety of adjuvant drugs can be used to enhance the effect of narcotics and to treat specific side effects of the disease or of therapy. For the terminally ill patient, a peaceful death with dignity should always be possible.
采用系统方法来确定疼痛原因并合理使用药物治疗是为癌症患者缓解疼痛的关键。阿司匹林、对乙酰氨基酚和非甾体抗炎药对轻至中度疼痛有效,并且它们能增强弱效口服麻醉剂(如可待因)的疗效。对于重度疼痛,吗啡是首选药物。可使用多种辅助药物来增强麻醉剂的效果,并治疗疾病或治疗产生的特定副作用。对于晚期患者,应始终有可能实现有尊严的安详离世。