Guo D, Wang Y, Fu W
Research Unit of Vascular Surgery, Zhongshan Hospital, Shanghai Medical University, Shanghai 200032, China.
Zhonghua Yi Xue Za Zhi. 2000 Feb;80(2):98-100.
To investigate the correlation between duplex scanning, magnetic resonance angiography (MRA), and digital subtraction angiography (DSA) in the evaluation of extracranial internal carotid artery (EICA) stenosis.
All the examinations mentioned-above were performed on 32 patients. According to NASCET, EICA stenosis were classified into four grades: mild (the diameter reduction < 30%), moderate (31% approximately 69%), severe (70% approximately 99%), and total occlusion.
One (3.1%) patient suffered from acute brain infarction after DSA. To compare duplex with DSA, Kappa = 0.78, and by the use of a severe or a greater than 30% stenosis as a positive study, the sensitivity, specificity and accuracy were 78%, 95%, 92% and 97%, 91%, 94%, respectively. To compare MRA with DSA, Kappa = 0.73, and with the same criteria, the sensitivity, specificity and accuracy were 78%, 90%, 89% and 97%, 91%, 94%, respectively. In the evaluation where the results of duplex and MRA were in agreement, to compare duplex + MRA with DSA, Kappa = 0.93, and the sensitivity, specificity and accuracy in the diagnosis of severe stenosis were 100%, 95% and 96%, and the accuracy in the diagnosis of > 30% stenosis was 100%.
There is good correlativity between duplex scanning, MRA and DSA in the examination of EICA stenosis. A combination of duplex and MRA with their results in agreement may ultimately eliminate the need of DSA in the evaluation of EICA stenosis.
探讨双功超声扫描、磁共振血管造影(MRA)和数字减影血管造影(DSA)在评估颅外颈内动脉(EICA)狭窄中的相关性。
对32例患者进行上述所有检查。根据北美症状性颈动脉内膜切除术试验(NASCET)标准,EICA狭窄分为四级:轻度(直径缩小<30%)、中度(31%至69%)、重度(70%至99%)和完全闭塞。
1例(3.1%)患者在DSA检查后发生急性脑梗死。双功超声与DSA比较,Kappa值=0.78,以重度或大于30%狭窄为阳性检查结果时,敏感性、特异性和准确性分别为78%、95%、92%以及97%、91%、94%。MRA与DSA比较,Kappa值=0.73,采用相同标准时,敏感性、特异性和准确性分别为78%、90%、89%以及97%、91%、94%。在双功超声和MRA结果一致的评估中,双功超声+MRA与DSA比较,Kappa值=0.93,重度狭窄诊断的敏感性、特异性和准确性分别为100%、95%、96%,>30%狭窄诊断的准确性为100%。
双功超声扫描、MRA和DSA在EICA狭窄检查中具有良好的相关性。双功超声和MRA结果一致的联合检查最终可能无需DSA来评估EICA狭窄。