Al'perovich P M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1975;75(9):1333-9.
In 138 patients 81 had multiple cancer metastasis into the brain and 57 -- singular. The main significance for the differentiation of singular or multiple cancer metastasis of the brain are clinical signs. Singular metastasis attaining a significant size may be expressed in monofocal symptomatology. In a small number (2 or 3) of metastasis there is usually a well expressed multifocal neurological symptomatology, inasmuch as they also attain a rather large size and are frequently located in both hemispheres or supra- and subtentorially. In a large amount of metastases, although they are small, they involve different parts of the hemispheres and consequently mental changes become more expressed. Hypertensive and focal symptoms are slightly expressed or may be absent altogether. For purposes of differentiating singular or multiple foci of special importance may be contrast methods of investigation (carotid angigoraphy) and EEG.
在138例患者中，81例有多发癌转移至脑，57例为单发。区分脑单发或多发癌转移的主要依据是临床体征。达到相当大小的单发转移瘤可能表现为单灶症状。少数（2个或3个）转移瘤通常有明显的多灶性神经症状，因为它们也长得相当大，且常位于双侧半球或幕上及幕下。在大量转移瘤的情况下，尽管它们很小，但累及半球的不同部位，因此精神改变更为明显。高血压和局灶性症状表现轻微或可能完全没有。用于区分单发或多发灶的特别重要的检查方法可能是造影检查（颈动脉血管造影）和脑电图。
