关于染色质中组蛋白的排列。
On the arrangement of histones in chromatin.
作者信息
Toczko K, Kaliński A, Zukowska-Niedźwiedź A
出版信息
Acta Biochim Pol. 1975;22(3):251-6.
PMID:1179912
Abstract
It was found that nucleoprotein particles formed after DNase I action on calf thymus chromatin contain single-stranded DNA fragments, associated with histones only by ionic linkages. These results suggest that histones in chromatin are bound ionically only to one polynucleotide strand of double-helical DNA, protecting it against nucleolytic attack.
摘要
研究发现，DNase I作用于小牛胸腺染色质后形成的核蛋白颗粒含有单链DNA片段，仅通过离子键与组蛋白结合。这些结果表明，染色质中的组蛋白仅通过离子键与双螺旋DNA的一条多核苷酸链结合，保护其免受核酸酶攻击。
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