Thomsen J, Zilstorff K
Acta Otolaryngol. 1975 Sep-Oct;80(3-4):276-82. doi: 10.3109/00016487509121328.
The clinical findings in 125 patients with surgically confirmed acoustic neuromas are presented, with special regard to the involvement of the intermedius nerve in the diagnosis. In assessing the function of the intermedius nerve the examination of the nasolacrimal reflex and the sensation of taste on the anterior two-thirds of the tongue are used. The methods of investigation are described in detail. The material consisted of 20 medium-sized and 105 large tumours; no intracanalicular tumor was found. Hearing loss was the initial symptom in 85% of the patients, 10% had tinitus and 4% vertigo as the first symptom. Apart from the VIII cranial nerve symptoms, a defective nasolacrimal reflex was the most significant evidence of cerebellopontine angle pathology. The test was positive in 65% of the medium-sized tumours, in the entire material, 85%. The figures are higher than the incidence of trigeminal nerve symptoms. This in contrast to the reports of most authors. The tests described are simple and quick to perform, and it is emphasized that they should be applied to all patients with unilateral hearing loss of unknown origin.
本文介绍了125例经手术确诊为听神经瘤患者的临床 findings，特别关注中间神经在诊断中的 involvement。在评估中间神经功能时，采用了鼻泪反射检查和舌前三分之二味觉检查。详细描述了研究方法。材料包括20例中型肿瘤和105例大型肿瘤；未发现管内肿瘤。85%的患者以听力损失为首发症状，10%以耳鸣、4%以眩晕为首发症状。除第八颅神经症状外，鼻泪反射缺陷是桥小脑角病变的最重要证据。该检查在65%的中型肿瘤中呈阳性，在整个材料中为85%。这些数字高于三叉神经症状的发生率。这与大多数作者的报告相反。所描述的检查操作简单、快速，强调应将其应用于所有不明原因单侧听力损失的患者。
