Wallenberg L R
Acta Physiol Scand. 1975 Sep;95(1):21-5. doi: 10.1111/j.1748-1716.1975.tb10019.x.
With clearance technique, changes in tubular reabsorption of solute free water (TcH2O), were studied in a group of 9 healthy hydropenic volunteers during a cold stress of 1 h at +15 degrees C. Increases were found in TcH2O and in fractional excretion of sodium and osmoles during cold. Since TcH2O was used as an index of sodium reabsorption in the ascending limb of Henle's loop, the findings indicated that under the conditions used in this study, the concentrating ability of the kidney was not negatively influenced by cold, despite a significant increase in arterial pressure. It is suggested that the reabsorption by the ascending limb of the loop was increased secondary to a reduced proximal tubular reabsorption of sodium.
采用清除技术，在9名健康禁水志愿者处于15摄氏度的冷应激状态1小时期间，研究了肾小管对无溶质水（TcH2O）重吸收的变化。结果发现，冷应激期间TcH2O以及钠和渗透摩尔分数排泄增加。由于TcH2O被用作亨利氏袢升支中钠重吸收的指标，这些发现表明，在本研究使用的条件下，尽管动脉压显著升高，但肾脏的浓缩能力并未受到冷应激的负面影响。研究表明，袢升支的重吸收增加是近端肾小管钠重吸收减少的继发结果。
