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肾移植受者肺部卡波西肉瘤的诊断挑战与管理

The diagnostic challenge and management of pulmonary Kaposi's sarcoma in renal transplant recipients.

作者信息

Krayem A B, Wali S O, Samman Y S

机构信息

Pulmonary Section, Department of Medicine, King Khalid National Guard Hospital, Jeddah, Kingdom of Saudi Arabia.

出版信息

Saudi Med J. 2001 Dec;22(12):1061-4.

Abstract

Kaposi's sarcoma is a multicentric low grade tumor that usually begins with the development of violaceous skin lesions and is associated with the presence of human herpes virus 8. Kaposi's sarcoma has been described in immunocompromised patients, particularly following renal transplantation, with cutaneous involvement being the most salient finding. Infectious and non-infectious pulmonary disorders in immunocompromised patients can simulate the radiological manifestations of pulmonary Kaposi's sarcoma. This report highlights the dilemma in reaching an accurate diagnosis of pulmonary Kaposi's sarcoma as a complication of immunosuppression post-renal transplant and reviews the management of immunosuppression related Kaposi's sarcoma.

摘要

卡波西肉瘤是一种多中心的低度肿瘤,通常始于紫红色皮肤病变的出现,并与人类疱疹病毒8的存在有关。卡波西肉瘤已在免疫功能低下的患者中被描述,尤其是在肾移植后,皮肤受累是最显著的表现。免疫功能低下患者的感染性和非感染性肺部疾病可模拟肺卡波西肉瘤的放射学表现。本报告强调了在准确诊断肾移植后免疫抑制并发症肺卡波西肉瘤时所面临的困境,并回顾了免疫抑制相关卡波西肉瘤的治疗。

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