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镰状细胞性状与妊娠:一家社区医院的经验综述

Sickle-cell trait and pregnancy: A review of a community hospital experience.

作者信息

Rimer B A

出版信息

Am J Obstet Gynecol. 1975 Sep 1;123(1):6-11. doi: 10.1016/0002-9378(75)90933-3.

DOI:10.1016/0002-9378(75)90933-3
PMID:1180285
Abstract

The obstetric experiences of 128 gravidas delivered at Charlotte Memorial Hospital in 1973 who, on hemoglobin electrophoresis, exhibited an SA pattern of hemoglobin are reviewed. In addition to previously reported complications of increased rates of pyelonephritis and refractory anemia, this group of patients exhibited a marked increase in premature rupture of membranes and prematurity. It is suggested that the routine screening procedures be used for discovering sickle-cell trait individuals and that they be categorized as "high-risk" obstetric patients because of the increased complication rates described here and by previous authors.

摘要

对1973年在夏洛特纪念医院分娩的128名孕妇的产科经历进行了回顾,这些孕妇经血红蛋白电泳显示为血红蛋白SA模式。除了先前报道的肾盂肾炎发病率增加和难治性贫血等并发症外,这组患者的胎膜早破和早产明显增加。建议采用常规筛查程序来发现镰状细胞性状个体,并由于此处及先前作者所述的并发症发生率增加,将他们归类为“高危”产科患者。

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Sickle cell trait diagnosis: clinical and social implications.镰状细胞性状诊断:临床及社会影响
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