Wu Sandra Jones, Tanphaichitr Artthapol, Ly Micki
Division of Dermatology, Ohio State University, Columbus, Ohio, USA.
Clin Podiatr Med Surg. 2002 Jan;19(1):65-78. doi: 10.1016/S0891-8422(03)00081-8.
Novel therapies for dermatologic diseases are now widely available to the clinician. The topical immune modulators tacrolimus and pimecrolimus are likely to change the way in which inflammatory dermatoses are treated. Antiviral and antitumor effects of imiquimod, another immune-response modifier, are being studied to determine the ways in which it may affect the treatment of cutaneous viral infections and skin cancers. New topical treatments for onychomycosis and the current lack of effective treatments for nondermatophyte onychomycosis indicate the need for more effective treatment for this common disease. Exciting developments in skin substitutes and growth factors for acute and chronic wound care hold much promise for the future.
临床医生现在可以广泛使用治疗皮肤病的新型疗法。外用免疫调节剂他克莫司和吡美莫司可能会改变炎症性皮肤病的治疗方式。另一种免疫反应调节剂咪喹莫特的抗病毒和抗肿瘤作用正在研究中,以确定其可能影响皮肤病毒感染和皮肤癌治疗的方式。甲癣的新型局部治疗方法以及目前缺乏针对非皮肤癣菌性甲癣的有效治疗方法,表明需要对这种常见疾病进行更有效的治疗。用于急性和慢性伤口护理的皮肤替代品和生长因子的激动人心的进展为未来带来了很大希望。