Anghileri L J
Arch Geschwulstforsch. 1975;45(3):219-31.
Calcium concentration in intra- and extracellular fluid from Ehrlich ascites tumor cells has been studied. The higher content of calcium in the outer cell fluid appears as a possible factor determining the behavior of the cell membrane. While in the cytoplasm macromolecular compounds such as lipo- and nucleoproteins seem to play an important role in calcium-binding, in the extracellular fluid calcium is likely to be bound to small molecules (presumably short chain polyphosphates). The significance of calcium-binding changes at the cell membrane level in the carcinogenesis and in the physiological behavior of the tumor cells is discussed.
对艾氏腹水癌细胞内外液中的钙浓度进行了研究。细胞外液中较高的钙含量似乎是决定细胞膜行为的一个可能因素。虽然在细胞质中，诸如脂蛋白和核蛋白等大分子化合物在钙结合中似乎起重要作用，但在细胞外液中，钙可能与小分子（大概是短链多磷酸盐）结合。讨论了细胞膜水平上钙结合变化在肿瘤发生和肿瘤细胞生理行为中的意义。
