Ptashekas R S
Arkh Patol. 1975;37(7):33-7.
Pathological anatomy of grafting artificial heart valves formed of the broad fascia of the hip in 5 patients was studied. The fate of a transplant depended upon conditions of its adaptation on a new place. In the case of an unfavourable outcome of transplantation there were observed decomposition of the connective-tissue fibres with degradation of collagen, their decomposition with formation of lacunes, inflammatory reactions, vascularization of the transplant and sclerosis thereof, which, all together, brought about deformation of a new valve. It was suggested that dystrophic and autoimmune mechanisms of destruction of the transplanted tissue were involved.
对5例采用臀阔筋膜制成的人工心脏瓣膜移植的病理解剖进行了研究。移植体的命运取决于其在新位置的适应情况。在移植结果不佳的情况下,观察到结缔组织纤维分解、胶原蛋白降解、形成腔隙、炎症反应、移植体血管化及其硬化,所有这些共同导致新瓣膜变形。研究表明,移植组织的营养不良和自身免疫破坏机制参与其中。