Kurtaran Amir, Traub Tatjana, Shapiro Brahm
Department of Nuclear Medicine, University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
Eur J Radiol. 2002 Feb;41(2):123-30. doi: 10.1016/s0720-048x(01)00442-9.
This article presents the well established scintigraphic imaging techniques of the adrenal glands. Both adrenocortical scintigraphy with [131]6beta-iodomethylnorcholesterol (NP-59) and adrenomedullary imaging with 131I or 123I-labelled metaiodobenzylguanidine (MIBG) as function-dependant imaging techniques provide functional metabolic information for lesion characterization. They enable the distinction between unilateral and bilateral adrenal lesions. Furthermore, they have the advantage of giving the possibility of a whole body evaluation with a single administration of the tracer without additional radiation dose. On the other hand, radiological imaging modalities provide excellent anatomical details which is essential for planning therapy. Both radiological and scintigraphic imaging methods of the adrenal glands are necessary and should, therefore, be considered complementary.
本文介绍了成熟的肾上腺闪烁成像技术。使用[131]6β-碘甲基去甲胆固醇（NP-59）的肾上腺皮质闪烁成像和使用131I或123I标记的间碘苄胍（MIBG）的肾上腺髓质成像作为功能依赖性成像技术，可为病变特征提供功能代谢信息。它们能够区分单侧和双侧肾上腺病变。此外，它们的优势在于单次注射示踪剂就有可能进行全身评估，而无需额外的辐射剂量。另一方面，放射成像模态可提供出色的解剖细节，这对于规划治疗至关重要。肾上腺的放射成像和闪烁成像方法都是必要的，因此应被视为互补的。
