Hausegger K A, Tiesenhausen K, Schedlbauer P, Oberwalder P, Tauss J, Rigler B
Department of Radiology, University Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria.
Cardiovasc Intervent Radiol. 2001 Sep-Oct;24(5):306-12. doi: 10.1007/s00270-001-0048-0.
To evaluate the feasibility of endoluminal stent-grafts in the treatment of acute type B aortic dissections.
In five patients with acute aortic type B dissections, sealing of the primary intimal tear with an endoluminal stent-graft was attempted. Indication for treatment was aneurysm formation in two patients and persistent pain in three patients. One of the latter also had an unstable dissection flap compromising the ostium of the superior mesenteric artery. The distance from the intimal tear to the left subclavian artery was <0.5 cm in four patients, who had typical type B dissections. In one patient with an atypical dissection the distance from the primary tear to the left subclavian artery was 4 cm. This patient had no re-entry tear. Talent tube grafts (World Medical Manufacturing Cooperation, Sunrise, FL, USA) were used in all patients.
Stent-graft insertion with sealing of the primary tear was successful in all patients. The proximal covered portion of the stent-graft was placed across the left subclavian artery in four patients (1x transposition of the left subclavian artery). Left arm perfusion was preserved via a subclavian steal phenomenon in the patients in whom the stent-graft covered the orifice of the left subclavian artery. The only procedural complication we observed was an asymptomatic segmental renal infarction in one patient. In the thoracic aorta thrombosis of the false aortic lumen occurred in all patients. In one patient the false lumen of the abdominal aorta thrombosed after 4 weeks; in the other three patients the status of the abdominal aorta remained unchanged compared with the situation prior to stent-graft insertion. As a late complication formation of a secondary aneurysm of the thoracic aorta was observed at the distal end of the stent-graft 3 months after the primary intervention. This aneurysm was treated by coaxial insertion of an additional stent-graft without complications.
Endoluminal treatment of acute type B aortic dissections seems to be an attractive alternative treatment to surgical repair. Thrombosis of the false lumen of the thoracic aorta can be induced if the primary tear is sealed with a stent-graft. This could protect the dissected thoracic aorta from delayed rupture.
评估腔内支架型人工血管治疗急性B型主动脉夹层的可行性。
对5例急性B型主动脉夹层患者尝试用腔内支架型人工血管封闭原发内膜破口。治疗指征为2例患者形成动脉瘤,3例患者持续疼痛。后者中有1例还存在不稳定的夹层瓣累及肠系膜上动脉开口。4例典型B型夹层患者的内膜破口至左锁骨下动脉的距离<0.5 cm。1例非典型夹层患者的原发破口至左锁骨下动脉的距离为4 cm。该患者无再入口破口。所有患者均使用Talent管状移植物(美国佛罗里达州日出市世界医疗制造公司)。
所有患者均成功植入支架型人工血管并封闭原发破口。4例患者的支架型人工血管近端覆盖部分跨过左锁骨下动脉(1例左锁骨下动脉移位)。在支架型人工血管覆盖左锁骨下动脉开口的患者中,通过锁骨下动脉窃血现象保留了左臂灌注。我们观察到的唯一手术并发症是1例患者出现无症状节段性肾梗死。所有患者的胸主动脉假腔均发生血栓形成。1例患者在4周后腹主动脉假腔形成血栓;其他3例患者腹主动脉的情况与植入支架型人工血管前相比无变化。作为晚期并发症,在初次干预3个月后,在支架型人工血管远端观察到胸主动脉继发性动脉瘤形成。该动脉瘤通过同轴植入额外的支架型人工血管进行治疗,无并发症发生。
腔内治疗急性B型主动脉夹层似乎是手术修复的一种有吸引力的替代治疗方法。如果用支架型人工血管封闭原发破口,可诱导胸主动脉假腔血栓形成。这可保护夹层的胸主动脉免于延迟破裂。