Chavan Ajay, Lotz Joachim, Oelert Frank, Galanski Michael, Haverich Axel, Karck Matthias
Department of Diagnostic Radiology, Hannover Medical School, Carl Neuberg Strasse 1, 30625, Hannover, Germany.
Eur Radiol. 2003 Nov;13(11):2521-34. doi: 10.1007/s00330-003-1936-2. Epub 2003 Jun 17.
Aortic dissection is most often a catastrophic medical emergency which, if untreated, can be potentially fatal. The intention of therapy in patients with aortic dissection is to prevent aortic rupture or aneurysm formation as well as to relieve branch vessel ischaemia. Patients with aortic dissection are often poor candidates for anaesthesia and surgery and the surgical procedure itself is challenging requiring thoracotomy, aortic cross clamping, blood transfusion as well as prolonged hospital stay in some cases. Operative mortality is especially high in patients with critical mesenteric or renal ischaemia. The past decade has experienced the emergence of a number of interventional radiological or minimally invasive techniques which have significantly improved the management of patients with aortic dissection. These include stent grafting for entry site closure to prevent aneurysmatic widening of the false lumen as well as percutaneous techniques such as balloon fenestration of the intimal flap and aortic true lumen stenting to alleviate branch vessel ischaemia. False lumen thrombosis following entry closure with stent grafts has been observed in 86-100% of patients, whereas percutaneous interventions are able to effectively relieve organ ischaemia in approximately 90% of the cases. In the years to come, it is to be expected that these endoluminal techniques will become the method of choice for treating most type-B dissections and will assist in significantly reducing the number of open surgical procedures required for type-A dissections. The intention of this article is to provide an overview of the current status of these endoluminal techniques based on our own experience as well as on a review of the relevant literature.
主动脉夹层通常是一种灾难性的医疗急症,若不治疗,可能会致命。治疗主动脉夹层患者的目的是预防主动脉破裂或动脉瘤形成,并缓解分支血管缺血。主动脉夹层患者往往不适合进行麻醉和手术,而且手术本身具有挑战性,需要开胸、主动脉交叉钳夹、输血,在某些情况下还需要延长住院时间。对于患有严重肠系膜或肾缺血的患者,手术死亡率尤其高。在过去十年中,出现了许多介入放射学或微创技术,这些技术显著改善了主动脉夹层患者的治疗。这些技术包括使用支架移植物封闭入口部位,以防止假腔动脉瘤样扩张,以及经皮技术,如内膜瓣球囊开窗和主动脉真腔支架置入术,以缓解分支血管缺血。使用支架移植物封闭入口后,86%至100%的患者出现了假腔血栓形成,而经皮介入治疗在大约90%的病例中能够有效缓解器官缺血。在未来几年,预计这些腔内技术将成为治疗大多数B型夹层的首选方法,并将有助于显著减少A型夹层所需的开放手术数量。本文旨在根据我们自己的经验以及对相关文献的回顾,概述这些腔内技术的现状。