Hovav Y, Yaffe H, Zentner B, Dan-Goor M, Almagor M
Department of Obstetrics and Gynecology, Bikur Cholim Hospital, Hadassah Mount Scopus Hospital, Jerusalem, Israel.
Hum Reprod. 2002 Feb;17(2):390-2. doi: 10.1093/humrep/17.2.390.
Electroejaculation has become an accepted form of semen procurement in men suffering from anejaculation. However, sperm in these ejaculates often exhibit low motility. In such cases, ICSI is offered to improve the possibility of successful pregnancy. Here we evaluate the fertilizing potential, using ICSI, of fresh and cryopreserved sperm obtained by transrectal electroejaculation from patients with psychogenic anejaculation.
A total of 25 men suffering from psychogenic anejaculation underwent 37 sessions of electroejaculation in combination with ICSI. In 17 patients fresh sperm (29 cycles, group I) was used, and in the other eight patients cryopreserved sperm (10 cycles, group II) was used.
A total of 155 oocytes were injected with fresh sperm with a fertilization rate of 55% (85/155). The pregnancy rate was 10% (3/29) per cycle. A total of 94 oocytes were injected with frozen-thawed sperm with a fertilization rate of 50% (47/94). The pregnancy rate was 40% (4/10) per cycle.
The fertilization and pregnancy rates with cryopreserved sperm from electroejaculation are at least as good as those of freshly obtained sperm. Therefore, when motile sperm is found in the thawed ejaculate, additional electroejaculation can be avoided.
电射精已成为治疗不射精男性获取精液的一种公认方法。然而,这些射精精液中的精子通常活力较低。在这种情况下,会采用卵胞浆内单精子注射(ICSI)来提高成功受孕的可能性。在此,我们评估经直肠电射精从心因性不射精患者获取的新鲜及冷冻保存精子,通过ICSI的受精潜能。
共有25名心因性不射精男性接受了37次电射精联合ICSI治疗。17例患者使用新鲜精子(29个周期,I组),另外8例患者使用冷冻保存精子(10个周期,II组)。
共向155个卵母细胞注射新鲜精子,受精率为55%(85/155)。每个周期的妊娠率为10%(3/29)。共向94个卵母细胞注射冻融精子,受精率为50%(47/94)。每个周期的妊娠率为40%(4/10)。
电射精冷冻保存精子的受精率和妊娠率至少与新鲜获取精子的受精率和妊娠率一样好。因此,当解冻精液中发现有活力精子时,可避免再次进行电射精。