Zhang Q, Zhang C, Wang J, Guan L, Yu H
Anhui College of Traditional Chinese Medicine, Hefer 230038.
Zhong Yao Cai. 2001 Oct;24(10):728-30.
To observe the nootropic effect of Rheum palmatum decoction in mice.
Step-down test.
Rheum palmatum decoction could increase learning and memory ability of old mice and also improve the impairments of memory acquisition, memory consolidation and memory retrieval induced by scopalamine, NaNO2 and 40% EtOH respectively in mice.
Rheum palmatum decoction contains the substances of increasing intelligence which may be substantial basis of the decoctions mainly containing Rheum palmatum theraping aphasia from apoplexy, senile dysmnesis, sequel from brain trauma, etc.
观察大黄水煎剂对小鼠的益智作用。
采用跳台试验。
大黄水煎剂可提高老年小鼠的学习记忆能力，还可改善东莨菪碱、亚硝酸钠和40%乙醇分别所致小鼠记忆获得、记忆巩固和记忆再现障碍。
大黄水煎剂含有益智成分，可能是大黄为主的方剂治疗中风失语、老年记忆力减退、脑外伤后遗症等的物质基础。
