Dyban A P, Chebotar' N A
Biull Eksp Biol Med. 1975 Aug;80(8):103-6.
Cytological preparations were made by Tarkovsky's method from 2335 rat oocytes obtained after an induced superodulation. The chromosomes could be counted exactly in 861 oocytes. In 797 oocytes (92.7%) euploidy (metaphase II with 21 chromosomes) and in 64 oocytes (7.5%) aneuploidy was found. 60 oocytes were hypoploid, but only 4 oocytes (0.4%) were hyperploid (with 22 chromosomes). Hypoploidy can often be due to the presence of artefacts. Probably the rate of spontaneous aneuploidy in rat oogenesis is about 0.8%, this being significantly lower than the rate of spontaneous aneuploidy in mice oogenesis.
采用塔尔科夫斯基方法,从诱导超排卵后获得的2335个大鼠卵母细胞制备细胞涂片。在861个卵母细胞中可以准确计数染色体。在797个卵母细胞(92.7%)中发现整倍体(有21条染色体的中期II),在64个卵母细胞(7.5%)中发现非整倍体。60个卵母细胞为亚二倍体,但只有4个卵母细胞(0.4%)为超二倍体(有22条染色体)。亚二倍体常常可能是由于人为因素的存在。大鼠卵子发生中自发非整倍体的发生率可能约为0.8%,这明显低于小鼠卵子发生中自发非整倍体的发生率。