Bykovskaia S N, Bykovskiĭ A F, Shepelenko A M
Biull Eksp Biol Med. 1975 Aug;80(8):113-6.
Immune lymphocytes sorbed on the surface of the target cells were characterized during the period of the first three hours of combined incubation by the presence of the electron-dense matrix, abundance of mitochondria and lipids; small lymphocytes had disseminated ribosome organized into polysomes in the medium lymphocytes forming individual cysterns of the granular endoplasmic reticulum in the large lymphocytes, this indicating active protein synthesis by these cells. There were also revealed cells of plasmatic type. Cells incubated with the PHA for one hour represented a homogenous population of small lymphocytes of the same size as the clear cytoplasm containing free ribosomes and individual mitochondria. The proportion of the medium lymphocytes and the blasts increased with increase of the incubation period. These are cells with the clear cytoplasm freely disseminated polyribosomes in which no developed granular endoplasmic reticulum was sometimes revealed. The presence of two types of cells whose ultrastructure reflected their functional characteristics is discussed.
在联合孵育的前三小时内，吸附在靶细胞表面的免疫淋巴细胞具有以下特征：存在电子致密基质、丰富的线粒体和脂质；小淋巴细胞有分散的核糖体，在中等大小淋巴细胞中聚合成多核糖体，在大淋巴细胞中形成颗粒内质网的单个池，这表明这些细胞有活跃的蛋白质合成。还发现了浆细胞样细胞。用PHA孵育一小时的细胞是大小相同的小淋巴细胞的同质群体，其细胞质清亮，含有游离核糖体和单个线粒体。随着孵育时间的增加，中等大小淋巴细胞和母细胞的比例增加。这些细胞的细胞质清亮，有多核糖体自由分散，有时未发现发达的颗粒内质网。文中讨论了两种超微结构反映其功能特征的细胞的存在情况。
